๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

The search for new triazole antifungal agents

โœ Scribed by Yigal Koltin; Christopher A Hitchcock

Book ID
104414899
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
932 KB
Volume
1
Category
Article
ISSN
1367-5931

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โœฆ Synopsis

The first generation antifungal agent triazoles, fluconazole and itraconazole, have revolutionised the treatment of serious fungal infections such as mucosal and invasive candidiasis and cryptococcal meningitis. However, the treatment of some fungal infections, particularly aspergillosis, is still far from satisfactory and thus there is an important requirement for new broad-spectrum antifungal agents. The new second generation triazoles voriconazole and SCH-56592 show considerable promise in achieving this goal in the near future.

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