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New Synthetic Technology for the Mild and Selective One-Carbon Homologation of Hindered Aldehydes in the Presence of Ketones

โœ Scribed by Nicolaou, K. C.; Vassilikogiannakis, Georgios; Kranich, Remo; Baran, Phil S.; Zhong, Yong-Li; Natarajan, Swaminathan


Book ID
120195654
Publisher
American Chemical Society
Year
2000
Tongue
English
Weight
284 KB
Volume
2
Category
Article
ISSN
1523-7060

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A convenient one-pot procedure for the s
โœ Mario Paglialunga Paradisi; Giampiero Pagani Zecchini; Giorgio Ortar ๐Ÿ“‚ Article ๐Ÿ“… 1980 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 212 KB

The title process has been accomplished by a three-step sequence involving protection of aldeh;de as the imine, in situ reduction of ketone with lithium tri-tert-butoxyaluminohydride, and regeneration of aldehyde on hydrolytic work-up. The preferential in situ ketalization or hydration of aldehydes