New Synthetic Route to Di- and Trisubstituted Epoxides
β Scribed by Dr. Willy Dumont; Prof. Dr. Alain Krief
- Publisher
- John Wiley and Sons
- Year
- 1975
- Tongue
- English
- Weight
- 218 KB
- Volume
- 14
- Category
- Article
- ISSN
- 0044-8249
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
Recclved 111 USA 16 January 1976; received in UK for publfcetlon 5 Febraq ~976) The rearrangement of trlalkylalkynylborate salts (I) has been induced by a variety of electrophlles, and the stereochemlcal outcome 1s a complex function of several factors, lncludlng the nature of the electrophlle, the
## Abstract For Abstract see ChemInform Abstract in Full Text.
## Abstract Starting from ethyl 2βcyclohexenβ1βcarboxylate (**3**) the total synthesis of the perhydrohistrionicotoxin intermediate **23** was achieved in 25% overallβyield. The two key steps involve a positionally specific addition of HOBr to the oximeβolefin **7** and the alkylation of bromooxime