Synthesis of deuterium labeled 1,3-dimet
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Kumiko Mamada; Takashi Furuta; Yasuji Kasuya
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Article
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1987
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John Wiley and Sons
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French
โ 334 KB
A synthetic procedure for l13-di(trideuteromethyl)uric acid is described. Deuterium labeling of the N-1 and N-3 positions w a s achieved by methylation of 4-amino-5carbethoxyuracil with di( trideuteromethy1)-sulfate followed by cyclization of the dimethylated intermediate by heating. The synthesis r