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New synthesis of DL-α- aminoacids from t-butyl N(diphenylmethylene) oxamate

✍ Scribed by J.P. Bazureau; D. Person; M. Le Corre


Book ID
104229556
Publisher
Elsevier Science
Year
1989
Tongue
French
Weight
180 KB
Volume
30
Category
Article
ISSN
0040-4039

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✦ Synopsis


The condensation of phosphorus ylids with t-butyl N(diphenylmethylene) oxamate gives 2-aza 1,3-dienes

; subsequent reduction with sodium cyanoborohydride provides protected a-aminoacids.


📜 SIMILAR VOLUMES


New synthesis of protected α-dehydro α-a
✍ J.P. Bazureau; M. Le Corre 📂 Article 📅 1988 🏛 Elsevier Science 🌐 French ⚖ 101 KB

the condensation of a phosphorus ylid with t-butoxalyl iminoether gives 3-carbobutoxy 2-aza 1,3-dienes ; subsequent reaction with hydriodic acid provides protected a-dehydro a-amino acids (1). Syntheses of a-amino acids from nucleophilic amino acid synthons A are well