New Synthesis of Bis-guanylhydrazone and Bis-thiosemicarbazone of Methylglyoxal (III).
β Scribed by N. A. Keiko; T. N. Mamashvili
- Publisher
- John Wiley and Sons
- Year
- 2005
- Weight
- 13 KB
- Volume
- 36
- Category
- Article
- ISSN
- 0931-7597
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## Abstract Methylglyoxal bis(guanylhydrazone), a cytostatic compound which apparently interferes with the metabolism and/or functions of the natural polyamines (spermidine and spermine), was effectively taken up by cultured human lymphocytic leukemia cells, rapidly resulting in the formation of a