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New synthesis of 3,5-disubstituted-5H-thiazolo[3,2-a]pyrimidine via ring annulation of 3,4-dihydropyrimidin-2(1H)-thione using alkynyl(aryl)iodonium salts

✍ Scribed by Shelke, Amol V.; Bhong, Bhagyashree Y.; Karade, Nandkishor N.

Book ID: 118210858
Publisher: Elsevier Science
Year: 2013
Tongue: French
Weight: 447 KB
Volume: 54
Category: Article
ISSN: 0040-4039
DOI: 10.1016/j.tetlet.2012.11.098

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## Abstract An efficient and convenient method for thiazolo[3,2‐a]pyrimidines from cyclization reaction of dihydropyrimidine‐thiones with α‐bromoacetone in aqueous media is described. © 2008 Wiley Periodicals, Inc. Heteroatom Chem 19:149–153, 2008; Published online in Wiley InterScience (www.inters