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New synthesis and reactions of indolizidine 167E and indolizidine derivatives

โœ Scribed by Shang-Shing P. Chou; Shan-Lun Chiang; Guan-Lin Huang; Bi-Shan Chiang; Ya-Chien Yu


Book ID
119375824
Publisher
Elsevier Science
Year
2013
Tongue
French
Weight
763 KB
Volume
69
Category
Article
ISSN
0040-4020

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Asymmetric Heck cyclization route to ind
โœ Kurt Kiewel; Mathew Tallant; Gary A Sulikowski ๐Ÿ“‚ Article ๐Ÿ“… 2001 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 85 KB

Asymmetric intramolecular Heck cyclization of endocyclic enamides occurs at room temperature to give indoloizidine and azaazulene ring systems in up to 86% enantiomeric excess. A synthesis of (+)-epiindolizidine 167B and formal synthesis of 5E,9Z-indolizidine 223AB is described.