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New structure model for the ATP-binding cassette multidrug transporter LmrA

โœ Scribed by Luca Federici; Barbara Woebking; Saroj Velamakanni; Richard A. Shilling; Ben Luisi; Hendrik W. van Veen


Book ID
113488290
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
635 KB
Volume
74
Category
Article
ISSN
0006-2952

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Multidrug resistance mediated by the ATP
โœ Susan P.C. Cole; Roger G. Deeley ๐Ÿ“‚ Article ๐Ÿ“… 1998 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 203 KB

Resistance to multiple natural product drugs associated with reduced drug accumulation in human tumor cells may be conferred by either the 170 kDa P-glycoprotein or the 190 kDa multidrug resistance protein, MRP. Both MRP and P-glycoprotein belong to the large and ancient ATP-binding cassette (ABC) s