New Strategy for the Synthesis of Iminoglycitols from Amino Acids.
✍ Scribed by Sauda Swaleh; Juergen Liebscher
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 46 KB
- Volume
- 33
- Category
- Article
- ISSN
- 0931-7597
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**Chemically synthesized α‐amino acids** are used to fortify foodstuffs and animal feeds. The drawbacks of former syntheses are avoided in the reaction sequence __(1)__→__(2)__→__(3)__ which leads, __e.g.__ to lysine in an overall yield of 52% (X Cl, Br; R^1^ Me, Et; M K, Na, Li) equation ima
## Abstract __The in vitro non‐natural amino acid mutagenesis method provides the opportunity to introduce non‐natural amino acids site‐specifically into proteins. To this end, a chemically synthesised aminoacylated dinucleotide is enzymatically ligated to a truncated suppressor transfer RNA. The l