New Synthesis of Amino Acids from Halogenated Carboxylic Esters

✍ Scribed by Prof. Dr. Franz Effenberger; Dr. Karlheinz Drauz

• Publisher: John Wiley and Sons
• Year: 1979
• Tongue: English
• Weight: 308 KB
• Volume: 18
• Category: Article
• ISSN: 0044-8249
• DOI: 10.1002/anie.197904741

✦ Synopsis

Chemically synthesized α‐amino acids are used to fortify foodstuffs and animal feeds. The drawbacks of former syntheses are avoided in the reaction sequence (1)→(2)→(3) which leads, e.g. to lysine in an overall yield of 52% (X  Cl, Br; R^1^  Me, Et; M  K, Na, Li)
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