A new strategy for directed protein clea
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Bernard Cuenoud; Theodore M. Tarasow; Alanna Schepartz
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Article
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1992
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Elsevier Science
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French
β 317 KB
Attachment of a Ni(ll)-glyglyhis chelate to trifluoperazine results in a molecule capable of cleaving cahnodulin at a single locus upon activation with a peracid . We reported recentlyl a molecule (TFE-Fe) capable of oxidative cleavage of the protein calmodulin .2 TFE-Fe consists of a trifluoperazi