New strategies for characterizing ancient proteins using matrix-assisted laser desorption ionization mass spectrometry
โ Scribed by Peggy H Ostrom; Michael Schall; Hasand Gandhi; Tun-Li Shen; Peter V Hauschka; John R Strahler; Douglas A Gage
- Book ID
- 117118643
- Publisher
- Elsevier Science
- Year
- 2000
- Tongue
- English
- Weight
- 312 KB
- Volume
- 64
- Category
- Article
- ISSN
- 0016-7037
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๐ SIMILAR VOLUMES
Three structurally related compounds, 4-hydroxy-3-methoxyphenylpyruvic acid (HMPPA), indole-3-pyruvic acid (IPA), and indole-3-glyoxylic acid have been evaluated as matrix-assisted laser desorption/ionization (MALDI) matrices. HMPPA and IPA were found to be effective matrices for MALDI-MS analysis o
## Abstract The application of matrixโassisted laser desorption/ionization mass spectrometry (MALDIโMS) for quantitative analysis was investigated with the use of internal standards. Three peptides/proteins in the mass range 1000โ12000 were tested and the effect of various internal standards was ev