𝔖 Bobbio Scriptorium
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New route to fatty acid esters developed


Publisher
Elsevier Science
Year
2003
Weight
31 KB
Volume
2003
Category
Article
ISSN
1351-4180

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The title compounds are prepared in one step from ester enolates and 3,3,3-trifluoropropene. The a-substituted 5,5-difluoro-4-pentenoic acid esters are susceptible to a second deprotonation and, on reaction with an electrophile, give access to the a-disubstituted analogues.