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New Pyrimido[5,4-b]indoles and [1]Benzothieno[3,2-d]pyrimidines: High Affinity Ligands for the α1-Adrenoreceptor Subtypes.

✍ Scribed by Giuseppe Romeo; Luisa Materia; Gabriella Marucci; Maria Modica; Valeria Pittala; Loredana Salerno; Maria Angela Siracusa; Michela Buccioni; Piero Angeli; Kenneth P. Minneman

Publisher
John Wiley and Sons
Year
2007
Weight
25 KB
Volume
38
Category
Article
ISSN
0931-7597

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✦ Synopsis

Abstract

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✍ G. Romeo; F. Russo; A. De Blasi 📂 Article 📅 2001 🏛 Journal of Heterocyclic Chemistry 🌐 English ⚖ 47 KB 👁 1 views

## Abstract A new series of 3‐[ω‐[4‐(4‐substituted phenyl)piperazin‐1‐yl]alkyl]‐5__H__‐pyrimido[5,4‐__b__]indole‐(1__H__,3__H__)‐2,4‐diones (**3–10** and **12–13**) were synthesized from the __N__‐(2‐chloroethyl)‐__N'__‐[3‐(2‐ethoxycarbonyl)indolyl] urea (**1**) or the __N__‐(3‐chloropropyl)‐__N'__