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New potent enkephalin analogs containing trifluoromethylamino acid residues

✍ Scribed by Iwao Ojima; Koji Kato; Fabian A. Jameison; John Conway; Kazuaki Nakahashi; Masaki Hagiwara; Tetsuhisa Miyamae; Hans E. Radunz

Book ID
108477094
Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
340 KB
Volume
2
Category
Article
ISSN
0960-894X

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## Abstract Six octapeptide bombesin (BN) analogs were synthesized by substituting α‐aminoisobutyric acid (Aib), in place of Ala^9^ or Gly^11^, or both, in the [D‐Phe^6^, __des__Met^14^]‐BN (6–14) sequence: D‐Phe^6^‐Gln^7^‐Trp^8^‐Ala^9^‐Val^10^‐Gly^11^‐His^12^‐Leu^13^‐NH~2~ (**P0**). Additionally,