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New polymorphism of the human T-cell receptorAV28S1gene segment

✍ Scribed by Anne Marie Moody; H. Reyburn; Nick Willcox; John Newsom-Davis

Publisher
Springer-Verlag
Year
1998
Tongue
English
Weight
169 KB
Volume
48
Category
Article
ISSN
0093-7711

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The T-cell receptor (Tcr) provides specificity for antigen recognition by its variable domain, primarily consisting of two germline encoded variable (I0 region gene segments. Thus it has been suggested that inherited polymorphisms in the TCRV gene segments could contribute to differential immune res