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New perspectives on endothelin-1 in atherosclerosis and diabetes mellitus

✍ Scribed by John Pernow; Alexey Shemyakin; Felix Böhm

Book ID
119318258
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
676 KB
Volume
91
Category
Article
ISSN
0024-3205

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Endothelin-1 is mainly synthesized by the vascular endothelial cells and acts on the vascular smooth muscle. Because of its vasoconstrictor and mitogenic effects it plays a role in the development of vascular diseases. In diabetes mellitus atherosclerosis is accelerated. The authors summarize the av