New Paradigms for Organic Catalysts: The First Organocatalytic Living Polymerization

✍ Scribed by Fredrik Nederberg; Eric F. Connor; Michael Möller; Thierry Glauser; James L. Hedrick

• Publisher: John Wiley and Sons
• Year: 2001
• Tongue: English
• Weight: 98 KB
• Volume: 40
• Category: Article
• ISSN: 0044-8249
• DOI: 10.1002/1521-3773(20010716)40:14<2712::aid-anie2712>3.0.co;2-z

✦ Synopsis

A metal-free approach to the living ring-opening polymerization (ROP, shown schematically) of lactide has been developed using strongly basic amines such as 4-(dimethylamino)pyridine as transesterification catalysts. These organic catalysts must be used in combination with a nucleophile such as an alcohol, which is the actual initiating species.