Hexafluoroacetone / N-Methylaspartic acid / N-Methylglutamic acid / N-Methyl-α-aminoadipic acid / N-Methylthiazol-4-yl-α-amino acids N-Methylaspartic acid derivatives and its homologues are acid derivative 9b by a Wolff rearrangement. A variety of homochiral N-methylamino acids, 5 and 12, and their
✦ LIBER ✦
New Organometallic Approach to Derivatives of α-Substituted Statines from N,N-Dibenzylaminoaldehydes.
✍ Scribed by Nicolas Le Carrer-Le Goff; Patrick Audin; Joelle Paris; Bernard Cazes
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 32 KB
- Volume
- 33
- Category
- Article
- ISSN
- 0931-7597
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✦ Synopsis
Abstract
For Abstract see ChemInform Abstract in Full Text.
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## Condensation of Dimethyl-3-methylglutaconate with α-Aminoaldehydes: A Straightforward Synthesis of New 2-Substituted Statines. -The reaction of the zinc enolate derived from diester (I) with chiral amino aldehydes (II) is investigated. At low temperature formation of undesired lactones is avoi