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New Neplanocin Analogues II. Enzymatic One-Step Synthesis and Antitumor Activity of 6′-(3-sn-Phosphatidyl)Neplanocin a Derivatives

✍ Scribed by Shuto, Satoshi; Ito, Hiromichi; Obara, Takumi; Nakagami, Keiji; Yaso, Masao; Yaginuma, Satoshi; Tsujino, Masatoshi; Saito, Tetsu; Matsuda, Akira; Ueda, Tohru


Book ID
126880457
Publisher
Taylor and Francis Group
Year
1992
Tongue
English
Weight
463 KB
Volume
11
Category
Article
ISSN
0732-8311

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ChemInform Abstract: Nucleosides and Nuc
✍ A. MATSUDA; ET AL. ET AL. 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 36 KB 👁 1 views

Nucleosides and Nucleotides. Part 154. New Neplanocin Analogues. Part 8. Synthesis and Biological Activity of 6'-C-Ethyl, -Ethenyl, and -Ethynyl Derivatives of Neplanocin A. -Reaction of the aldehyde (I) with ethynylmagnesium bromide gives the corresponding 6'-ethynyl derivative as a diastereomeric