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New minimum length requirement for a T cell epitope for experimental allergic neuritis

โœ Scribed by Tsaiwei Olee; Henry C. Powell; Steven W. Brostoff


Book ID
119107541
Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
303 KB
Volume
27
Category
Article
ISSN
0165-5728

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Studies from our laboratory have shown that region 69-84 (synthetic peptide S49S) of myelin basic protein (MBP) defines an encephalitogenic sequence for experimental allergic encephalomyelitis (EAE) in Lewis rats. The most potent EAE inducers are the guinea pig MBP (Gp-MBP) and region 69-84, known a