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Peptide 53–78 of myelin P2 protein is a T cell epitope for the induction of experimental autoimmune neuritis

✍ Scribed by Abdolmohamad Rostami; Shahik K. Gregorian


Book ID
113134697
Publisher
Elsevier Science
Year
1991
Tongue
English
Weight
609 KB
Volume
132
Category
Article
ISSN
0008-8749

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Studies from our laboratory have shown that region 69-84 (synthetic peptide S49S) of myelin basic protein (MBP) defines an encephalitogenic sequence for experimental allergic encephalomyelitis (EAE) in Lewis rats. The most potent EAE inducers are the guinea pig MBP (Gp-MBP) and region 69-84, known a