New method of synthesis of 1,5-benzodiazepin-2-ones from 4-hydroxycoumarin
✍ Scribed by Maǎmar Hamdi; Odile Grech; Reine Sakellariou; Vincent Spézale
- Book ID
- 112130916
- Publisher
- Journal of Heterocyclic Chemistry
- Year
- 1994
- Tongue
- English
- Weight
- 227 KB
- Volume
- 31
- Category
- Article
- ISSN
- 0022-152X
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📜 SIMILAR VOLUMES
A solid-phase synthesis ofpolysubstituted 1,5-benzodiazepin-2-ones is described. Resinbound 4-fluoro-3-nitrobanzoic acid was reacted with different ~amino acids, followed by nitro group reduction and formation of the seven-membered ring. Subsequent alkylations at N(5) and N(1) afforded the title com
UDC 547.892.07:543. 422.25'51 4-Styryl-2,3-dihydro-iH-l,5-benzodiazepin-2-ones were synthesized and their structure was established by means of PMR spectra and mass spectroscopy. There is no unequivocal information on the structure of the reaction products of 4methyl-2,3-dihydro-iH-l,5-benzodiazepi