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New method of peptide cleavage based on Edman degradation

✍ Scribed by Remigiusz Bąchor, Alicja Kluczyk, Piotr Stefanowicz…

Book ID
120750569
Publisher
Springer
Year
2013
Tongue
English
Weight
308 KB
Volume
17
Category
Article
ISSN
1381-1991

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✍ G.C. Barrett; A.A.E. Penglis; A.J. Penrose; D.E. Wright 📂 Article 📅 1985 🏛 Elsevier Science 🌐 French ⚖ 237 KB

Terminal N-(p henyl thiocarbamoyl)peptides, formed under mild basic conditions in the first stage ("coupling") of the Edman degradation of peptides, are shown to undergo cleavage at the first peptide bond under similar conditions at higher temperatures. The usual products of the