✦ LIBER ✦
Edman Stepwise degradation of polypeptides: a new strategy employing mild basic cleavage conditions
✍ Scribed by G.C. Barrett; A.A.E. Penglis; A.J. Penrose; D.E. Wright
- Book ID
- 104228891
- Publisher
- Elsevier Science
- Year
- 1985
- Tongue
- French
- Weight
- 237 KB
- Volume
- 26
- Category
- Article
- ISSN
- 0040-4039
No coin nor oath required. For personal study only.
✦ Synopsis
Terminal N-(p henyl thiocarbamoyl)peptides, formed under mild basic conditions in the first stage ("coupling") of the Edman degradation of peptides, are shown to undergo cleavage at the first peptide bond under similar conditions at higher temperatures. The usual products of the