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New method for synthesis of carbalkoxyalkylamidodialkyl phosphates

โœ Scribed by N. P. Grechkin; L. K. Nikonorova


Book ID
112438094
Publisher
Springer
Year
1969
Tongue
English
Weight
117 KB
Volume
18
Category
Article
ISSN
1573-9171

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## Abstract A simple method of chemical phosphorylation for modified nucleosides with [^32^P]orthophosphoric acid in the presence of BrCN is described. The yields of 5โ€ฒโ€[^32^P]nucleoside monophosphates achieved are 50โ€“65% at nominal specific radioactivities of ca. 1000โ€‰Ci/mmol. The mechanism of pho