𝔖 Bobbio Scriptorium
✦   LIBER   ✦

New Macrocycles with Planar Chirality—Synthesis and Determination of Absolute Configurations

✍ Scribed by Jarosław Kalisiak; Paweł Skowronek; Jacek Gawroński; Janusz Jurczak

Publisher
John Wiley and Sons
Year
2006
Tongue
English
Weight
359 KB
Volume
12
Category
Article
ISSN
0947-6539

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

A versatile system for preparing macrocyclic compounds with planar chirality is presented. In this system chiral diazacoronands are synthesized readily from lariat‐type diesters 13 and 14 and unsymmetrical diamines 7, 8, 12, 15, and 16 under non‐high‐dilution conditions. The title compounds were subjected to structural analysis by X‐ray crystallography and circular dichroism spectroscopy, and absolute configurations for two representative examples (compounds 2 and 3) were assigned by molecular modeling. The correctness of the theoretical approach was verified by the crystallographic results obtained experimentally.

📜 SIMILAR VOLUMES

Total Synthesis and Determination of the
Total Synthesis and Determination of the Absolute Configuration of (+)-Omaezakianol
✍ Yoshiki Morimoto; Tatsuya Okita; Hitomi Kambara 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 339 KB 👁 2 views

## Abstract **Synthese als Beweis**: Die erste asymmetrische Totalsynthese des marinen tetracyclischen Oxasqualenoids (+)‐Omaezakianol umfasst eine konvergente Olefin‐Kreuzmetathese zwischen einem Monotetrahydrofuran‐Fragment und einem Triepoxyalken sowie eine Oxacyclisierungskaskade eines Triepoxy

Synthesis and Determination of the Absol
Synthesis and Determination of the Absolute Configuration of Pyrenophorin and Vermiculin
✍ Prof. Dr. Dieter Seebach; Dipl.-Chem. Bernhard Seuring; Dr. Hans-Otto Kalinowski 📂 Article 📅 1977 🏛 John Wiley and Sons 🌐 English ⚖ 259 KB

vacuum distillation with exclusion of moisture affords 41.5 g (72 %) of ( 2), b. p. 55 "C/0.3 torr. ## 1 -Methyl-2-bis(trimethylsilyl)amino-2-trimethylsilylimino-3trimethylsilyl-4-tris(dimethylamino)-l,3,2,4A'-diazadiphosphetidine ( 3 ) : Compound (2) (1.92 g, 10 mmol) is added dropwise to a stirr