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New ligands for copper-catalyzed C–N coupling reactions with aryl halides

✍ Scribed by Chen, Dong; Yang, Kai; Xiang, Hua; Jiang, Sheng

Book ID
118015668
Publisher
Elsevier Science
Year
2012
Tongue
French
Weight
918 KB
Volume
53
Category
Article
ISSN
0040-4039

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Copper-catalyzed C–N coupling reactions
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✍ Nasani Narendar; Sivan Velmathi 📂 Article 📅 2009 🏛 Elsevier Science 🌐 French ⚖ 186 KB

We have developed an efficient method for the preparation of enantiopure N-aryl-a-amino acids via copper-catalyzed N-arylation of a-amino acids and aryl halides under microwave irradiation. This protocol only needs less than 30 min to obtain the products, which are far superior to those obtained und