New insights into the organization of the basal ganglia
β Scribed by James B. Koprich; Tom H. Johnston; Philippe Huot; Susan H. Fox; Jonathan M. Brotchie
- Book ID
- 107545691
- Publisher
- Springer
- Year
- 2009
- Tongue
- English
- Weight
- 236 KB
- Volume
- 9
- Category
- Article
- ISSN
- 1528-4042
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
Dopamine (DA) neurons exist in two activity states; either spontaneously firing or quiescent and nonfiring. When faced with a behavioral demand, the quiescent DA neurons can be activated to facilitate normal motor output. Levodopa appears to increase DA output by activating these nonfiring neurons;
The current model of the organization of basal ganglia was proposed in the 1980s following key observations made on animal models of neurodegenerative diseases and patients who had hypo-or hyperkinetic movement disorders.I4 This model rapidly became the ultimate way of interpreting how basal ganglia