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New insights into the human 5-HT4 receptor binding site: exploration of a hydrophobic pocket

✍ Scribed by Lucie Rivail; Mireille Giner; Monique Gastineau; Magali Berthouze; Jean-Louis Soulier; Rodolphe Fischmeister; Frank Lezoualc'h; Bernard Maigret; Sames Sicsic; Isabelle Berque-Bestel


Book ID
110008468
Publisher
Nature Publishing Group
Year
2004
Tongue
English
Weight
405 KB
Volume
143
Category
Article
ISSN
0007-1188

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The anatomical localization of 5-HT(4) receptor mRNA and 5-HT(4) receptor protein was examined in sections of post-mortem human brain by in situ hybridization histochemistry and radioligand receptor autoradiography. In the in situ hybridization study, the highest levels of 5-HT(4) receptor mRNA were