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New indole alkaloids from the leaves of Malaysian Mitragyna speciosa

✍ Scribed by Hiromitsu Takayama; Mika Kurihara; Mariko Kitajima; Ikram M. Said; Norio Aimi


Publisher
Elsevier Science
Year
1998
Tongue
French
Weight
420 KB
Volume
54
Category
Article
ISSN
0040-4020

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✦ Synopsis


Three new monoterpenoid indole alkaloids, i.e., 3,4,5,6-tetradehydromitragynine, mitralactonal, and mitrasulgynine carrying a sulfonate function, were isolated, together with seven known compounds, from the leaves ofMitragyna speciosa native to Malaysia.


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## Abstract Three new indole alkaloids, 11,12‐de(methylenedioxy)danuphylline (**1**), methyl (2__Ξ²__,11__Ξ²__,12__Ξ²__,19__Ξ±__)‐6,7‐didehydro‐8,21‐dioxo‐11,21‐cycloaspidospermidine‐2‐carboxylate (**2**), and (2__Ξ²__,5__Ξ²__)‐aspidofractinin‐16‐ol (**3**) were isolated from __Kopsia officinalis__, toge