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New graphical representation of a DNA sequence based on the ordered dinucleotides and its application to sequence analysis

✍ Scribed by Yujuan Huang; Tianming Wang

Publisher
John Wiley and Sons
Year
2011
Tongue
English
Weight
735 KB
Volume
112
Category
Article
ISSN
0020-7608

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✦ Synopsis

Abstract

Graphical representation of a DNA sequence is a powerful tool for basic biological research. Based on the ordered dinucleotides, we propose a novel three dimensional (3D) graphical representation without circuit or degeneracy. Simultaneously, we derive the projection curve of the 3D graph. These two curves have good visualization for longer DNA sequences. The utility of the proposed curves is illustrated by mutation analysis, similarity analysis, and evolutionary relationships of different species. The results indicate that our method is efficient and powerful. Β© 2011 Wiley Periodicals, Inc. Int J Quantum Chem, 2012

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