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New genes in old sequence: a strategy for finding genes in the bacterial genome

✍ Scribed by Mark Borodovsky; Eugene V. Koonin; Kenneth E. Rudd

Book ID
113408635
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
784 KB
Volume
19
Category
Article
ISSN
0968-0004

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frequently several million base pairs and as, at a rough estimate, the average density of genes transcribed in a given tissue is only four per one million base pairs, the isolation of a disease gene would be facilitated by focussing efforts on expressed sequences. Specifically, identifying sequences