New Enantioselective Synthesis of (10R,11S)-(+)-Juvenile Hormones I and II
β Scribed by Tomoko Okochi; Kenji Mori
- Publisher
- John Wiley and Sons
- Year
- 2001
- Tongue
- English
- Weight
- 314 KB
- Volume
- 2001
- Category
- Article
- ISSN
- 1434-193X
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Samples of racemic [10-3H] juvenile hormone 111 (methyl (2~,6~)-lO,ll-epoxy-3,7,11-trimethyl-2,6-dodecadienoate) and [lo-3 Hljuvenile hormone 0 (methyl (2E,6~,10~)-3,7-diethyl-l0,1l-epoxy-ll-methyl-2,6-tridecadienoate~were prepared by NaB H4 reduction of the corresponding 1 I-chloro-lo-oxo ("chlorok
## Abstract Radiolabeled opticallyβactive JH III bisepoxide ([^3^H]β(10__R__)βJHB~3~) was synthesized from [12β^3^H] (10__R__)βJH III using dimethyldioxirane to give an inseparable mixture of diastereomers with the __trans__β6,7βepoxide __syn__ or __anti__ to the existing 10,11βepoxide. [^3^H]β(10_