Novel Bleomycin Analogues: Synthesis, An
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Zhi-Dong Xu; Min Wang; Su-Long Xiao; Yan-Juan Zhang; Ming Yang
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Article
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2004
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John Wiley and Sons
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German
β 155 KB
## Abstract The novel analogues **11**β**16** of bleomycin A~6~ (**3**) were obtained by selective protection of the primaryβamine function of the __Ξ²__βaminoalaninamide moiety of **3** by means of coordination with Cu^II^ ions, condensation with an aliphatic or aromatic acid Rβ²COOH in the presence