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New cytotoxic isomalabaricane-type sesterterpenes from the New Caledonian marine sponge Rhabdastrella globostellata

✍ Scribed by Marie-Lise Bourguet-Kondracki; Arlette Longeon; Cécile Debitus; Michèle Guyot

Publisher
Elsevier Science
Year
2000
Tongue
French
Weight
168 KB
Volume
41
Category
Article
ISSN
0040-4039

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✦ Synopsis

Four new cytotoxic isomalabaricane sesterterpenes, aurorals 1-4, have been isolated from the New Caledonian marine sponge Rhabdastrella globostellata. Their structures were established by spectroscopic data including 1D and 2D techniques. These compounds were found to exhibit cytotoxic activity on KB cells.

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New cytotoxic sesterterpenes from the Ne
New cytotoxic sesterterpenes from the New Caledonian marine sponge Petrosaspongia nigra (Bergquist)
✍ Luigi Gomez Paloma; Antonio Randazzo; Luigi Minale; Cécile Debitus; Christos Rou 📂 Article 📅 1997 🏛 Elsevier Science 🌐 French ⚖ 475 KB

Along with two known cheilanthane sesterterpene lactones, 1 and 2, eight new related sesterterpenes (3-10) and two new nor-sesterterpenes (11 and 12) have been isolated from the New Caledonian marine sponge Petrosaspongia nigra Bergquist 1995 (new genus, new species). Their structures were determine