New cyclobutyl analogs of nucleosides. Part 2. Synthesis and antiviral evaluation of 2-amino-7-[3,3-bis (hydroxymethyl)cyclobut-1-yl]-3H,7H-pyrrolo-[2,3-d]pyrimidin-4-one and of cyclobutyl analogs of the pyrimidine nucleosides
β Scribed by H Boumchita; M Legraverend; A Zerial; M Lemaitre; C Huel; E Bisagni
- Publisher
- Elsevier Science
- Year
- 1991
- Tongue
- French
- Weight
- 539 KB
- Volume
- 26
- Category
- Article
- ISSN
- 0223-5234
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## Abstract A series of nonβnucleosides **9β47** were synthesized. Compounds **1β4** were reacted with formic acid (85%) to afford compounds **5β8**. Then, the latter compounds were reacted with alkyl halides **aβf** (2βbromopropane, 2βbromobutane, benzyl bromide, benzyl chloromethyl ether, chlorom
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