New Classes of Environmental Tumor Promoters: Indole Alkaloids and Polyacetates
β Scribed by Hirota Fujiki, Takashi Sugimura and Richard E. Moore
- Book ID
- 124275886
- Publisher
- Environmental Health Information Service
- Year
- 1983
- Tongue
- English
- Weight
- 1020 KB
- Volume
- 50
- Category
- Article
- ISSN
- 0091-6765
- DOI
- 10.2307/3429537
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Human peripheral blood monocytes were cultured and exposed to plant diterpenes, indole alkaloids and polyacetates with various degrees of tumor-promoting activity. The effect of the above-mentioned encounter on monocyte function was examined, as expressed by H2O2 production and lysis of dog erythroc
Indolactam I. a new congener of indole alkaloid tumor promoter teleocidins, was isolated from S treptoverticillium blastmyceticum, and was shown to be biosynthesized from N-methyl-L-isoleucyl-L-tryptophanol. (-)-Indolactam V,t.2) an active fragment of indole alkaloid tumor promoter teleocidins.3)