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New chromosome abnormalities and lack of BCL-6 gene rearrangements in Argentinean diffuse large B-cell lymphomas

โœ Scribed by Roxana Cerretini; Maria F. Noriega; Marina Narbaitz; Irma Slavutsky

Book ID
114793993
Publisher
John Wiley and Sons
Year
2006
Tongue
English
Weight
433 KB
Volume
76
Category
Article
ISSN
0902-4441

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## Abstract ## BACKGROUND In Western populations, rearrangement of the __BCL__โ€6 gene can be identified in 20โ€“40% of patients with diffuse large Bโ€cell lymphoma (DLBCL). Analysis of the __BCL__โ€6 gene has revealed the presence of point mutations or small deletions in 70% of DLBCL tumors; however,