New chiral phosphinamide catalysts for highly enantioselective reduction of ketones
β Scribed by Mark P. Gamble; John R. Studley; Martin Wills
- Publisher
- Elsevier Science
- Year
- 1996
- Tongue
- French
- Weight
- 226 KB
- Volume
- 37
- Category
- Article
- ISSN
- 0040-4039
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π SIMILAR VOLUMES
The condensation of o-(diphenylphosphino)benzaldehyde and various chiral diamine gives a series of diimino-diphosphine tetradentate ligands, which are reduced with excess NaBH4 in refluxing ethanol to afford the corresponding diaminodiphosphine ligands in good yield. The reactivity of these ligands
A new serica of 1,3,2-ox&rolidine catalysts sukituted in pmition 4 by the (CHa)sC(CHa), group (n=2,3,4, 5) were ryntheuized and applied to the borane reduction of prochired ketones. The relationship between catalyst structure and enantioselectivity wan d i s c d . ## Keywordr, Oxazaborolidine, en