New chiral ferrocenyl building blocks for asymmetric reactions
β Scribed by Lothar Schwink; Paul Knochel
- Publisher
- Elsevier Science
- Year
- 1997
- Tongue
- French
- Weight
- 258 KB
- Volume
- 38
- Category
- Article
- ISSN
- 0040-4039
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β¦ Synopsis
The new C2-symmetrical ferrocenyl amines 2 and 3 are easily prepared starting from the ketones 4. Their utility is demonstrated for enantioselective deprotonation reactions and highly diastereoselective alkylations of the amides 7.
π SIMILAR VOLUMES
AS chiral building block for the synthesis of natural cyclopentanoid substances, an optically pure and stable ketal of 4-hydroxycyclopent-2-en-I-one was prepared by enantioselective enzymatic hydrolysis of the corresponding racemic acetate. (1982) 480.
## Abstract Enantiopure NβsulfinylβΞ΄βaminoβΞ²βketoesters and isoquinolones, prepared from sulfinimines (Nβsulfinyl imines) are a new class of polyfunctionalized chiral building blocks. These building blocks provide easy access to enantiomerically pure, functionalized piperidines and tetrahydroisoqui