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New catalytic ultrasound method for derivatization of 11-nor-Δ9-tetrahydrocannabinol-9-carboxylic acid in urine, with analysis by GC-MS/MS

✍ Scribed by Vanessa de M. Prata; Elissandro S. Emídio; Haroldo S. Dorea


Book ID
113021928
Publisher
Springer
Year
2012
Tongue
English
Weight
414 KB
Volume
403
Category
Article
ISSN
1618-2650

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Rapid and robust confirmation and quanti
✍ Gabriele Zanchetti; Ivan Floris; Alberto Piccinotti; Silvia Tameni; Aldo Poletti 📂 Article 📅 2012 🏛 John Wiley and Sons 🌐 English ⚖ 327 KB

A method for the rapid and robust confirmation of 11‐nor‐∆9‐tetrahydrocannabinol‐9‐carboxylic acid (THCA) in urine involving basic hydrolysis with NaOH and direct injection of the hydrolysate in a column‐switching LC‐MS‐MS system was developed and validated. THCA‐d3 was used as internal standard. De