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A validated GC–MS method for the determination of Δ9-tetrahydrocannabinol and 11-nor-Δ9-tetrahydrocannabinol-9-carboxylic acid in bile samples

✍ Scribed by Ioannis Papoutsis; Panagiota Nikolaou; Artemisia Dona; Constantinos Pistos; Maria Stefanidou; Chara Spiliopoulou; Sotirios Athanaselis

Book ID
107344087
Publisher
Springer Japan
Year
2011
Tongue
English
Weight
272 KB
Volume
30
Category
Article
ISSN
1860-8965

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Studies on the metabolism of the Δ9-tetrahydrocannabinol precursor Δ9-tetrahydrocannabinolic acid A (Δ9-THCA-A) in rat using LC-MS/MS, LC-QTOF MS and GC-MS techniques
✍ Julia Jung; Markus R. Meyer; Hans H. Maurer; Christian Neusüß; Wolfgang Weinmann 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 215 KB

## Abstract In __Cannabis sativa__, Δ9‐Tetrahydrocannabinolic acid‐A (Δ9‐THCA‐A) is the non‐psychoactive precursor of Δ9‐tetrahydrocannabinol (Δ9‐THC). In fresh plant material, about 90% of the total Δ9‐THC is available as Δ9‐THCA‐A. When heated (smoked or baked), Δ9‐THCA‐A is only partially conver