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New Building Blocks for Tackling the Synthesis of Polyhydroxylated Piperidines: Expeditious Synthesis of Amino Derivatives in the 1-Deoxynojirimycin Series

✍ Scribed by Poupon, Erwan; Luong, Binh-Xuyen; Chiaroni, Angèle; Kunesch, Nicole; Husson, Henri-Philippe


Book ID
126335889
Publisher
American Chemical Society
Year
2000
Tongue
English
Weight
56 KB
Volume
65
Category
Article
ISSN
0022-3263

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(S)-Leucine and [(S)-1-(1-Naphthyl)ethyl
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Two selectors derived from [(S)-1-(1-naphthyl)ethyl]amine and (S)-leucine have been chemically bonded to one another and the resulting chiral auxiliary linked covalently to silica gel, to produce a new chiral stationary phase (CSP) for the HPLC resolution of enantiomers. The CSP is able to separate