An Easy Access to 1-Azaspiropentane-2-ca
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Markus Tamm; Michael Thutewohl; Carsten B. Ricker; M. Teresa Bes; Armin de Meijer
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Article
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1999
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John Wiley and Sons
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English
⚖ 212 KB
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Azaspiropentanecarboxamides 10 and 12 are formed with good (27-59%, 12-48%), while the corresponding esters 9 could only be obtained in poor yields (4-14%). The new αremarkable ease in two steps in a one-pot operation from methyl 2-chloro-2-cyclopropylideneacetate (4) by addition of amino acid amide