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New betulinic acid derivatives as potent proteasome inhibitors

✍ Scribed by Keduo Qian; Sang-Yong Kim; Hsin-Yi Hung; Li Huang; Chin-Ho Chen; Kuo-Hsiung Lee


Book ID
113495998
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
320 KB
Volume
21
Category
Article
ISSN
0960-894X

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πŸ“œ SIMILAR VOLUMES


Betulin and ursolic acid synthetic deriv
✍ Oxana B. Kazakova; Gul’nara V. Giniyatullina; Emil Yu. Yamansarov; Genrikh A. To πŸ“‚ Article πŸ“… 2010 πŸ› Elsevier Science 🌐 English βš– 187 KB

The synthesis of new betulin and ursolic acid derivatives and evaluation of their antiviral activity in vitro is reported. Betulin was modified at positions C-3, C-20 and C-28 to afford the derivatives with nicotinoyl-, methoxycynnamoyl-, alkyne and aminopropoxy-2-cyanoethyl-moieties. The two stage