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New benzothieno[3,2-d]-1,2,3-triazines with antiproliferative activity: Synthesis, spectroscopic studies, and biological activity

✍ Scribed by Lauria, Antonino; Alfio, Alessia; Bonsignore, Riccardo; Gentile, Carla; Martorana, Annamaria; Gennaro, Giuseppe; Barone, Giampaolo; Terenzi, Alessio; Almerico, Anna Maria


Book ID
124150494
Publisher
Elsevier Science
Year
2014
Tongue
English
Weight
826 KB
Volume
24
Category
Article
ISSN
0960-894X

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Synthesis and biological activity of 1-,
✍ Francesco Guerrera; Loredana Salerno; Maria Concetta SarvΓ ; Maria Angela Siracus πŸ“‚ Article πŸ“… 1999 πŸ› Journal of Heterocyclic Chemistry 🌐 English βš– 376 KB

## Abstract A series of new 1‐, 2‐ and 3‐piperazinylbenzothieno[2,3‐__d__]triazole derivatives structurally related to Trazodone were prepared and tested for their antiserotonergic, antiadrenergic and antihistaminergic __in vitro__ activities together with their analgesic __in vivo__ activity by us