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New approach to the synthesis of 6-ketosteroids via organoiron complexes.

✍ Scribed by Enrico Mincione; Anthony J. Pearson; Paolo Bovicelli; Malcolm Chandler; Geoffrey C. Heywood


Publisher
Elsevier Science
Year
1981
Tongue
French
Weight
159 KB
Volume
22
Category
Article
ISSN
0040-4039

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✦ Synopsis


New Methodology is descrrbed for the synthesis 6_ketosteroids, of potential value for the synthesis of 8-ecdysone, via tricarbonyl (4-methoxy-1-methylcyclohexadienyl)


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New approach to aspidospermine total syn
✍ Anthony J. Pearson πŸ“‚ Article πŸ“… 1981 πŸ› Elsevier Science 🌐 French βš– 193 KB

The conversion of p-ethylanisole, via the tricarbonyl(diene)-iron complex (3), to the bicyclic amino ketone (2), which is a known precursor for aspidospermine total synthesis, is described. The synthetic route demonstrates the stability of the diene-Fe(C0)3 unit to a number of useful synthetic trans