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New and Efficient Synthesis of an Amino Acid for Preparing Phosphine-Functionalized Peptidomimetics

✍ Scribed by Porte, Alexander M.; van der Donk, Wilfred A.; Burgess, Kevin

Book ID
126160259
Publisher
American Chemical Society
Year
1998
Tongue
English
Weight
54 KB
Volume
63
Category
Article
ISSN
0022-3263

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Simple and effective preparation of amin
Simple and effective preparation of amino sulfonylureas from amino acids: application to the synthesis of amino sulfonylurea-containing peptidomimetics
✍ Roman Ε ink; Anamarija Zega πŸ“‚ Article πŸ“… 2008 πŸ› Elsevier Science 🌐 French βš– 102 KB

Several amino sulfonylureas have been synthesized, starting from amino acids. The synthetic procedure is simple affording high yields of products under mild conditions. Furthermore, it is shown that these compounds can be incorporated into a peptide sequence.